Cut-off and toxicity levels for drugs-of-abuse testing
This table summarizes information useful in the interpretation of drugs of abuse assays. It was developed by Daniel M. Baer, MD, professor emeritus of pathology, Oregon HealthSciences University, Portland, OR., and Richard A. Paulson, MT(ASCP), supervisor of toxicology lab, VA Medical Center, Portland, OR.

Drug (and trade name)
Street name
Detectable duration in urine after last use
Urine cut-off points for reporting positive*
Toxic blood level
Blood level after usual use
STIMULANTS

Cocaine

Coke
Crack
Flake
Snow
Benzoylecgonine 3 days after single use; 4 days after prolonged use. 300 ng/mL (S)(2)
150ng/mL (C)(4)
> 1 ug/mL 100-200ng.mL
Amphetamine (Benzadrine, Dexedrine) Speed
Bennies
Uppers
Dexies`
48 hours after single use; 7-10 days after prolonged use. 1,000 ng/mL (S)(2)
500 ng/mL (C)(4)
0.5-1.0 ug/mL 30-50ng/mL
Methamphetamine (Desoxyn, Methadrine) Speed
Meth
Crystal
Ice
Doe
48 hours after single use; 7-10 days after prolonged use. 1,000ng/mL (S)(2)
500 ng/mL (C)(4)
0.1-1.0 ug/mL 20-60 ng/mL
Methaphenidate (Ritalin) 80% excreted within 24 hours. Therapeutic dose not detected in urine. 500 ng/mL (S)(2)
200 ng.mL (C)(3)
100-500 ng/mL 15-50 ng/mL
Phenmetrazine (Preludin) 20% excreted within 24 hours 1,000 ng/mL (S)(1)
100 ng/mL (C)(3)
0.5-4 ug/mL 60-80 ng/mL
BARBITURATES

Pentobarbital (Nembutal)

Goof balls
Downers
Nembies
Yelow jackets
Yellow submarine
2 days 1,000 ng/mL (S)(2)
200 ng/mL (C)(4)
> 11.0 ug/mL <10 ug/mL
Secobarbitol (Seconal) Bullets
Pink ladies
Reds
2 days 200 ng/mL (S)(2)
200 ng/mL (C)(4)
5-15 ug/mL <10ug/mL
Amobarbital Blue angler
Blue birds
Goof balls
Stumbler
2 days 2,000 ng/mL (S)(2)
200 ng/mL (C)(4)
>20 ug/mL
Butabarbital (Butisol) Goof balls
Candy
Peanuts
Stoppers
2 days 1,000 ng/mL (S)(2)
200 ng/mL (C)(4)
>20 ug/mL
Butalbital (Fiorinal) Goof balls
Sleepers
Stoppers
Peanuts
2 days 3,000 ng/mL (S)(2)
200 ng/mL (C)(4)
>20 ug/mL
Phenobarbital Barbs
Downers
1-3 weeks 3,000 ng/mL (S)(2)
200 ng/mL (C)(4)
>40 ug/mL 10-40 ug/mL
ALCOHOL

Ethanol

Booze
Hootch
< 1 day 10 mg/dL 100-400 mg/dL 10-50 mg/dL
Methanol < 1 day 5 mg/dL >20 mg/dL 0.15 mg/dL
Isopropanol Rubbing alcohol <1 day 5 mg/dL 40-200 mg/dL 10 mg/dL
OPIATES

Heroin

Smack
Horse
White lady
Skag
2 days as metabolite. 2000 ng/mL >200 ng/mL
Morphine (Duramorph) M
Junk
Morpho
White stuff
2 days 2000 ng/mL >200 ng/mL 50-200 ng/mL
Methadone (Dolophine, Amidone) Methadose 3 days 300 ng/mL (S)(2)
150 ng/mL (C)(4)
1-2 ug/mL 150-400 ng/mL
Meperidine (Demerol, Pethidine, Mepergan) Fortis
Demies
200 ng/mL (S)(3)
200 ng/mL (C)(4)
>1000 ng/mL 50-250 ng/mL
Codeine, Analgesics with codeine Rabo
School boy
2 days 2000 ng/mL >1.1 ug/mL 50-100 ng/mL
Propoxyphene (Darvon, Darvocet-N) Yellow footballs 6 hours to 2 days 300 ng/mL (S)(2) >500 ng/mL 100-500 ng/mL
HALLUCINOGENIC DRUGS

Lysergic acid, diethylamide, LSD

Acid
Microdot
White lightning
3 days 0.1 ng/mL (S)(5)
5 pg/mL (C)(4)
2-30 ng/mL 1-5 ng/mL
Marijuana and cannabinoids Marijuana
Hashish
Bhang
Ganja
Sensemilla
Single use 2-7 days
Prolonged use 1-2 months
100 ng/mL (S)(2)
15 ng/mg (C)(4)
50-200 ng/mL
Phencyclidine PCP
Angel dust
Killer weed
Hog
Single use 1 week
Prolonged use 2 weeks
25 ng/mL (S)(2)
25 ng/mL (C)(4)
1 mg/mL 75-250 ng/mL
Ketamine (Ketalar) Jets
Super acid
Special LA coke
500 ng/mL (S)(1)
350 ng/mL (C)(3)
1-6 ug/mL
Amphetamine analogs DOM
STP
Diazepam (Valium) Single use not detectable
Prolonged use 5-7 days, can be up to 30 days
200 ng/mL (S)(2)
200 ng/mL (C)(4)
Drug plus metabolite
>3 ug/mL
Drug plus metabolite
0.7-1.8 ug/mL
Oxazepam (Serax) Single use not detectable
Prolonged use 5-7 days
200 ng/mL (S)(2)
200 ng/mL (C)(4)
>1.4 ug/mL 0.2-1.4 ug/mL

*Commonly accepted cut-off values; may be different for specific jurisdictions and methods. Sensititivity/cut-off data are from method literature and package inserts.

(S) = Screening cut off
(C) = Confirmation cut off
(1) Thin-layer chromatography (TLC)
(2) EMIT
(3) High-performance liquid chromatography (HPLC)
(4) Mass spectrometry (MS)
(5) Radioimmunoassay (RIA)

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