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mAMP

Methamphetamine

MDMA

D,L Methylenedioxyamphetamine

OPI

Morphine, Codeine

PCP

Phencyclidine

TCA

Nortriptyline

The following results are tabulated from these clinical studies:

%Agreement with Commercial Kit

AMP

BAR

BZO

COC

THC

MTD

Positive Agreement

97%

>99%

90%

95%

98%

99%

Negative Agreement

100%

>99%

97%

>99%

100%

>99%

Total Results

98%

99%

94%

98%

99%

>99%

mAMP

MDMA

MOP

OPI

PCP

TCA*

Positive Agreement

98%

100%

100%

>99%

98%

95%

Negative Agreement

100%

99%

100%

>99%

100%

>99%

Total Results

99%

99%

100%

>99%

99%

99%

%Agreement with GC/MS

AMP

BAR

BZO

COC

THC

MTD

Positive Agreement

97%

>99%

96%

96%

97%

99%

Negative Agreement

95%

>99%

96%

>90%

88%

>94%

Total Results

96%

99%

96%

93%

91%

>96%

mAMP

MDMA

MOP

OPI

PCP

TCA*

Positive Agreement

99%

96%

100%

>99%

100%

>99%

Negative Agreement

94%

98%

94%

>90%

97%

89%

Total Results/p>

96%

97%

97%

>95%

98%

91%

Forty (40) clinical samples for each drug were run using each of the Split-Specimen Cup by an untrained operator at a Professional Point of Care site. Based on GC/MS data, the operator obtained statistically similar Positive Agreement, Negative Agreement and Overall Agreement rates as trained laboratory personnel. *Note: TCA was based on HPLC data.

A study was conducted at three physician offices by untrained operators using three different lots of product to demonstrate the within run, between run and between operator precision. An identical panel of coded specimens. containing drugs at the concentration of + 50% and ± 25% cut-off level, was labeled, blinded and tested at each site. The results are given below:

AMPHETAMINE (AMP)

Amphetamine conc. (ng/mL)

n per site

Site A

SiteB

SiteC

-

+

-

+

-

+

0

5

5

0

5

0

5

0

500

5

5

0

4

1

5

:

750

5

5

0

1

4

1

-

1,250

5

0

5

0

5

0

5

1,500

5

0

5

0

5

0

5

BARBITURATES (BAR)

Secobarbital conc. (ng/mL)

n per site

Site A

Site B

SiteC

-

+

-

+

-

+

0

5

5

0

5

0

5

0

150

5

4

1

5

0

5

0

225

5

1

4

4

1

5

0

375

5

0

5

0

5

2

3

450

5

0

5

0

5

1

4

BENZODIAZEPINES (BZO)

Oxazepam conc. (ng/mL)

n per site

Site A

SiteB

SiteC

-

+

-

+

-

+

0

5

5

0

5

0

5

0

150

5

4

1

3

2

4

1

225

5

2

3

4

1

2

3

375

5

0

5

0

5

3

2

450

5

0

5

0

5

1

4